Regenerated silk fibroin using protic ionic liquids solvents: towards an all-ionic-liquid process for producing silk with tunable properties.

نویسندگان

  • Nicolas Goujon
  • Xungai Wang
  • Rangam Rajkowa
  • Nolene Byrne
چکیده

We have shown that protic ionic liquids, pILs, are effective coagulation solvents for the regenerated of silk fibroin, RSF. We show that the choice of pIL has a dramatic effect on the composition of the RSF. Additionally the use of pILs as the coagulator eliminates the need for volatile organic solvents in silk processing.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The degradation behavior of silk fibroin derived from different ionic liquid solvents

Establishing an appropriate degradation rate is critical for tissue engineering scaffolds. In this study, the degradation rate of silk fibroin threedimensional scaffolds was regulated by changing the molecular weight (MW) of the silk fibroin. The solubility of silk fibroin depends primarily on the ionic ability of the slovent to dissolve silk fibroin, therefore, we regulated the MW of the silk ...

متن کامل

Catalytic Role of Ionic Liquids for Dissolution and Degradation of Biomacromolecules

Natural biomacromolecules constitute a diverse feedstock, including carbohydrate-based polysaccharides (cellulose, hemicellulose, starch, agarose, and Konjac glucomannan) together with lignin — extracted mainly from biomass — and other protein based polymers, namely keratin, chitin, chitosan, and silk fibroin. The complex and heterogeneous chemical structure of biomacromolecules makes them diff...

متن کامل

Fabrication and characterization of Eri silk fibers-based sponges for biomedical application.

UNLABELLED Cocoon-derived semi-domesticated Eri silk fibers still lack exploitation for tissue engineering applications due to their poor solubility using conventional methods. The present work explores the ability to process cocoon fibers of non-mulberry Eri silk (Samia/Philosamia ricini) into sponges through a green approach using ionic liquid (IL)--1-buthyl-imidazolium acetate as a solvent. ...

متن کامل

Production of Curcumin-Loaded Silk Fibroin Nanoparticles for Cancer Therapy

Curcumin, extracted from the rhizome of Curcuma longa, has been widely used in medicine for centuries due to its anti-inflammatory, anti-cancer, anti-oxidant and anti-microbial effects. However, its bioavailability during treatments is poor because of its low solubility in water, slow dissolution rate and rapid intestinal metabolism. For these reasons, improving the therapeutic efficiency of cu...

متن کامل

New for old. Password to the thermodynamics of the protic ionic liquids.

Activity coefficients at infinite dilution of some common solvents in a protic ionic liquid ethylammonium nitrate have been measured using well established gas-chromatography-method. This method was possible to apply due to extremely low vapour pressure of ethylammonium nitrate at temperatures below 100 °C. Activity coefficients and separation factors were compared with those for aprotic ionic ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 48 9  شماره 

صفحات  -

تاریخ انتشار 2012